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- Title
Multiple, Novel Biologically Active Endophytic Actinomycetes Isolated from Upper Amazonian Rainforests.
- Authors
Bascom-Slack, Carol A.; Cong Ma; Moore, Emily; Babbs, Beatrice; Fenn, Kathleen; Greene, Joshua S.; Hann, Bradley D.; Keehner, Jocelyn; Kelley-Swift, Elizabeth G.; Kembaiyan, Vivek; Sun Jin Lee; Puyao Li; Light, David Y.; Lin, Emily H.; Schorn, Michelle A.; Vekhter, Daniel; Boulanger, Lori-Ann; Hess, W. M.; Vargas, Percy Núñez; Strobel, Gary A.
- Abstract
Microbial biodiversity provides an increasingly important source of medically and industrially useful compounds. We have isolated 14 actinomycete species from a collection of approximately 300 plant stem samples from the upper Amazonian rainforest in Peru. All of the cultured isolates produce substances with inhibitory activity directed at a range of potential fungal and bacterial pathogens. For some organisms, this activity is very broad in spectrum while other organisms show specific activity against a limited number of organisms. Two of these organisms preferentially inhibit bacterial test organisms over eukaryotic organisms. rDNA sequence analysis indicates that these organisms are not equivalent to any other cultured deposits in GenBank. Our results provide evidence of the untapped biodiversity in the form of biologically active microbes present within the tissues of higher plants.
- Subjects
BIODIVERSITY; ACTINOBACTERIA; PLANT stems; RAIN forests; FUNGI; PATHOGENIC microorganisms
- Publication
Microbial Ecology, 2009, Vol 58, Issue 2, p374
- ISSN
0095-3628
- Publication type
Article
- DOI
10.1007/s00248-009-9494-z