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- Title
Advances in Organic Fluorescent Probes for Intracellular Zn 2+ Detection and Bioimaging.
- Authors
Chen, Yi
- Abstract
Zinc ions (Zn2+) play a key role in maintaining and regulating protein structures and functions. To better understand the intracellular Zn2+ homeostasis and signaling role, various fluorescent sensors have been developed that allow the monitoring of Zn2+ concentrations and bioimaging in live cells in real time. This review highlights the recent development of organic fluorescent probes for the detection and imaging of intracellular Zn2+, including the design and construction of the probes, fluorescent response mechanisms, and their applications to intracellular Zn2+ detection and imaging on-site. Finally, the current challenges and prospects are discussed.
- Subjects
FLUORESCENT probes; ZINC ions; PROTEIN structure; HOMEOSTASIS; CHEMORECEPTORS
- Publication
Molecules, 2024, Vol 29, Issue 11, p2542
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules29112542