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- Title
Stress response pathways, toxicity pathways and adverse outcome pathways.
- Authors
Jennings, Paul
- Abstract
The author reflects on the ambiguities and misconceptions on stress response pathways, toxicity pathways, and adverse outcome pathways. He thinks that the identification of these pathways can unravel the intricate interconnections in toxicology and how cells react to cellular perturbations. The author adds that knowledge of stress response pathways can lead to the development of superior models for safety assessment and will open new pharmaceutical targets for disease prevention and treatment.
- Subjects
IMMUNE response; TOXICOGENOMICS; MOLECULAR toxicology; PREVENTIVE medicine; THERAPEUTICS
- Publication
Archives of Toxicology, 2013, Vol 87, Issue 1, p13
- ISSN
0340-5761
- Publication type
Editorial
- DOI
10.1007/s00204-012-0974-4