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- Title
Admission Body Temperature in Critically Ill Patients as an Independent Risk Predictor for Overall Outcome.
- Authors
Erkens, Ralf; Wernly, Bernhard; Masyuk, Maryna; Muessig, Johanna M.; Franz, Marcus; Schulze, Paul Christian; Lichtenauer, Michael; Kelm, Malte; Jung, Christian; Muessig, Johanna M; Schulze, Paul Christian
- Abstract
<bold>Introduction: </bold>Body temperature (BT) abnormalities are frequently observed in critically ill patients. We aimed to assess admission BT in a heterogeneous critically ill patient population admitted to an intensive care unit (ICU) as a prognostic parameter for intra-ICU and long-term mortality.<bold>Methods: </bold>A total of 6,514 medical patients (64 ± 15 years) admitted to a German ICU between 2004 and 2009 were included. A follow-up of patients was performed retrospectively. The association of admission BT with both intra-ICU and long-term mortality was investigated by logistic regression.<bold>Results: </bold>Patients with hypothermia (<36°C BT) were clinically worse and had more pronounced signs of multi-organ failure. Admission BT was associated with adverse overall outcome, with a 2-fold increase for hyperthermia (mortality 12%; odds ratio [OR] 1.80, 95% confidence interval [CI] 1.43-2.26; p < 0.001), and a 4-fold increase for the risk of hypothermia (mortality 24%; OR 4.05, 95% CI 3.38-4.85; p < 0.001) with respect to intra-ICU and long-term mortality. Moreover, hypothermia was even more harmful than hyperthermia, and both were strongly associated with intra-ICU mortality, especially in patients admitted with acute coronary syndrome (hypothermia: hazard ratio 6.12, 95% CI 4.12-9.11; p < 0.001; hyperthermia: OR 2.70, 95% CI 1.52-4.79; p< 0.001).<bold>Conclusion: </bold>Admission BT is an independent risk predictor for both overall intra-ICU and long-term mortality in critically ill patients admitted to an ICU. Therefore, BT at admission might not only serve as a parameter for individual risk stratification but can also influence individual therapeutic decision-making.
- Subjects
BODY temperature; CRITICALLY ill; ACUTE coronary syndrome; INTENSIVE care units; FEVER
- Publication
Medical Principles & Practice, 2020, Vol 29, Issue 4, p389
- ISSN
1011-7571
- Publication type
journal article
- DOI
10.1159/000505126