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- Title
Chemoselective iodination of 6-substituted imidazo[1,2-a]pyridine.
- Authors
Zhao, Chunshen; Li, Fei; Yang, Shuo; Liu, Li; Huang, Zhuyan; Chai, Huifang
- Abstract
<graphic></graphic>3- and 8-Iodoimidazo[1,2-a]pyridines were synthesized from imidazo[1,2-a]pyridine under different substitution conditions. The molecular electrostatic potential calculations were performed to investigate the chemoselectivity of the substitution reaction. The molecular structures of the target compounds were characterized by single crystal X-ray diffraction analysis.
- Subjects
PYRIDINE synthesis; IMIDAZOPYRIDINES; MOLECULAR structure; ELECTROSTATICS; IODINATION; CHEMOSELECTIVITY; SUBSTITUTION reactions
- Publication
Chemistry of Heterocyclic Compounds, 2018, Vol 54, Issue 5, p568
- ISSN
0009-3122
- Publication type
Article
- DOI
10.1007/s10593-018-2307-x