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- Title
Influence of postmortem time on the outcome of blood cultures among cadaveric tissue donors.
- Authors
Saegeman, V.; Verhaegen, J.; Lismont, D.; Verduyckt, B.; Rijdt, T.; Ectors, N.
- Abstract
Tissue banks provide tissues of human cadaver donors for transplantation. The maximal time limit for tissue retrieval has been set at 24 h postmortem. This study aimed at evaluating the evidence for this limit from a microbiological point of view. The delay of growth in postmortem blood cultures, the identification of the species isolated and clinical/environmental factors were investigated among 100 potential tissue donors. No significant difference was found in the rate of donors with grown blood cultures within (25/65=38%) compared with after (24/65=37%) 24 h of death. Coagulase-negative staphylococci and gastro-intestinal microorganisms were isolated within and after 24 h of death. Two factors—antimicrobial therapy and “delay before body cooling”—were significantly inversely related with donors’ blood culture results. From a microbiological point of view, there is no evidence for avoiding tissue retrieval among donors after 24 h of death.
- Subjects
AUTOPSY; TISSUE banks; TRANSPLANTATION of organs, tissues, etc.; ORGAN donation; MICROBIOLOGY; BLOOD coagulation; STAPHYLOCOCCAL diseases; GASTROINTESTINAL diseases; SAFETY
- Publication
European Journal of Clinical Microbiology & Infectious Diseases, 2009, Vol 28, Issue 2, p161
- ISSN
0934-9723
- Publication type
Article
- DOI
10.1007/s10096-008-0609-0