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- Title
Synthesis, Characterization and Biological Evaluation of Novel Diesters of 4,4'-Dihydroxy Azoxy Benzene with Long Chain Carboxylic Acids.
- Authors
Shehzadi, Sumaira; Siddiqi, Humaira Masood; Qasim, Malik Muhammed; Fawad, Musfirah; Manan, Abdul; Khan, Naeema; Saleem, Samreen; Bashir, Farah; Mirza, Bushra
- Abstract
Synthesis of novel symmetrical azoxy diesters have been prepared by the reaction of 4,4'-dihydroxyazoxy benzene with aliphatic acid halides of varying chain lengths. The synthesized compounds have been characterized by spectral and analytical data. These symmetrical azoxy diesters exhibit good antifungal activity against six fungal strains (Mucor species, Aspergillus niger, Aspergillus flavus, Alternaria solani, Fusarium solani and Aspergillus fumigatus) and antitumor activities while no significant antibacterial activity has been observed. These synthesized compounds are also potent free radical scavengers.
- Subjects
AZOXY compounds; BENZENE; CARBOXYLIC acids; ANTIFUNGAL agents; ASPERGILLUS niger; LIQUID crystalline solvents
- Publication
Journal of the Chemical Society of Pakistan, 2014, Vol 36, Issue 3, p462
- ISSN
0253-5106
- Publication type
Article