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- Title
Single nucleotide polymorphisms and linkage disequilibrium analysis of three HSP90 family genes in cattle.
- Authors
Yang, Bai‐Gao; Duan, Xing‐Hai; E, Guang‐Xin
- Abstract
Along with the impact of global warming, heat stress has become an important factor that threatens livestock production.[1] This not only results in a decline in the productivity of dairy cows and the quality of milk products but also causes disorders in their immune system.[[2]]The Droughtmaster is a heat-tolerant cattle breed that was developed through crossbreeding Brahman and Shorthorn cattle in Australia.[4] In this study, Droughtmaster cattle were used as an experimental population and compared with cattle breeds not bred for heat tolerance to screen the genetic polymorphisms and LD pattern differences of known heat-stress-related genes. The LD analysis did not detect any significantly different linkage patterns ( I D i ') in the I HSP90AA1 i and I HSP90AB1 i genes of the three cattle breeds (Tables S4 & S5, Figs S1 & S2). Table S2 Tests for HWE at 12 SNPs of three cattle breedsTable S3 Pair-wise FST estimates at 12 SNPs between three cattle breeds.
- Subjects
SINGLE nucleotide polymorphisms; LINKAGE disequilibrium; PHYSIOLOGICAL effects of heat; GENE families; CATTLE; BREEDING; CATTLE diseases
- Publication
Animal Genetics, 2019, Vol 50, Issue 6, p784
- ISSN
0268-9146
- Publication type
Article
- DOI
10.1111/age.12847