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- Title
Sensitive Matters: The World Health Organisation and Antibiotic Resistance Testing, 1945–1975.
- Authors
Gradmann, Christoph
- Abstract
The paper assesses the development of antibiotic resistance diagnostics after 1945. In the 1950s, demand for such testing led to the adaptation of procedures from experimental pharmacology and bacterial genetics to the needs of clinical microbiology. Further developments were influenced by stakeholders in clinical medicine, public health and industry. These changes are viewed through the lens of a 1960s World Health Organisation (WHO)-initiated research project, and the ways in which it developed over time. Driven forward by the Swedish medical microbiologist Hans Ericsson, this project attempted to frame resistance diagnostics in relation to the needs of public health, a standardisation of diagnostic tools and with regard to therapeutic rationalism. These objectives were swiftly combined with that of raising the professional status of clinical microbiology. Such aspirations, however, ran counter to industrial interest. Early in the 1970s standardisation instead remained confined to a single element in the diagnostic process: a small paper disc containing antibiotics. Ironically, Ericsson, who had pushed for a broader standardisation of diagnostic processes, ultimately found himself embarking on a career as a commercial producer of those discs.
- Subjects
ANTIBIOTICS testing; DRUG resistance; MEDICAL microbiology; DIAGNOSTIC microbiology; HISTORY of pharmacology; EXPERIMENTAL pharmacology; INTERNATIONAL cooperation on public health; WORLD Health Organization; MICROBIOLOGISTS; ERICSSON, Hans; SHERRIS, John; TWENTIETH century; HISTORY
- Publication
Social History of Medicine, 2013, Vol 26, Issue 3, p555
- ISSN
0951-631X
- Publication type
Article
- DOI
10.1093/shm/hkt018