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- Title
Clinical and Molecular Relationships between COVID-19 and Feline Infectious Peritonitis (FIP).
- Authors
Sweet, Arjun N.; André, Nicole M.; Stout, Alison E.; Licitra, Beth N.; Whittaker, Gary R.
- Abstract
The emergence of severe acute respiratory syndrome 2 (SARS-CoV-2) has led the medical and scientific community to address questions surrounding the pathogenesis and clinical presentation of COVID-19; however, relevant clinical models outside of humans are still lacking. In felines, a ubiquitous coronavirus, described as feline coronavirus (FCoV), can present as feline infectious peritonitis (FIP)—a leading cause of mortality in young cats that is characterized as a severe, systemic inflammation. The diverse extrapulmonary signs of FIP and rapidly progressive disease course, coupled with a closely related etiologic agent, present a degree of overlap with COVID-19. This paper will explore the molecular and clinical relationships between FIP and COVID-19. While key differences between the two syndromes exist, these similarities support further examination of feline coronaviruses as a naturally occurring clinical model for coronavirus disease in humans.
- Subjects
MIDDLE East respiratory syndrome; COVID-19; PERITONITIS; DISEASE progression; SYMPTOMS
- Publication
Viruses (1999-4915), 2022, Vol 14, Issue 3, p481
- ISSN
1999-4915
- Publication type
Article
- DOI
10.3390/v14030481