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- Title
Case Report Tuberculosis-like lesions arising from the use of Freund's complete adjuvant in an owl monkey ( Aotus sp.).
- Authors
Málaga, Carlos A.; Weller, Richard E.; Broderson, J. Roger; Gozalo, Alfonso S.
- Abstract
An apparently normal, non-tuberculin-reacting, splenectomized owl monkey presented tuberculosis-like lesions of the lung at necropsy. Histological and bacteriological examination failed to demonstrate the presence of acid-fast organisms. Retrospective inquiry showed the animal had been inoculated using complete Freund's Adjuvant during a malaria vaccine trial. Lesions observed were compatible with lipid embolism of the adjuvant in the lungs.
- Subjects
THREE-striped night monkey; VETERINARY autopsy; IMMUNOLOGICAL adjuvants; MALARIA; LUNGS; VACCINES; VACCINATION
- Publication
Journal of Medical Primatology, 2004, Vol 33, Issue 2, p109
- ISSN
0047-2565
- Publication type
Article
- DOI
10.1111/j.1600-0684.2004.00060.x