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- Title
The heretotrimeric G protein subunit Gαi is present on mitochondria
- Authors
Lyssand, John S.; Bajjalieh, Sandra M.
- Abstract
Abstract: Receptors that signal through heretotrimeric GTP binding (G) proteins mediate the majority of intercellular communication. Recent evidence suggests that receptors acting through G proteins also transfer signals across the nuclear membrane. Here we present cell fractionation and immunolabeling data showing that the heretotrimeric G protein subunit Gαi is associated with mitochondria. This finding suggests that G protein receptor signaling may be a feature common to all membranes.
- Subjects
MEMBRANE proteins; G proteins; CELL communication; MITOCHONDRIA
- Publication
FEBS Letters, 2007, Vol 581, Issue 30, p5765
- ISSN
0014-5793
- Publication type
Article
- DOI
10.1016/j.febslet.2007.11.044