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- Title
Left ventricular volumes and mass in marathon runners and their association with cardiovascular risk factors.
- Authors
Kai Nassenstein; Frank Breuckmann; Nils Lehmann; Axel Schmermund; Peter Hunold; Martina Broecker-Preuss; Torleif Sandner; Martin Halle; Klaus Mann; Karl-Heinz Jöckel; Gerd Heusch; Thomas Budde; Raimund Erbel; Jörg Barkhausen; Stefan Möhlenkamp
- Abstract
Abstract  Background To assess left ventricular volumes and mass by cardiac magnetic resonance imaging in relation to conventional cardiovascular risk factors and coronary atherosclerotic plaque burden in master marathon runners aged â¥50 years. Methods Cardiac MRI was performed in 105 clinically healthy male marathon runners (mean age 57.3 ± 5.7 years, range 50â71 years) on a 1.5 T MR system (Avanto, Siemens, Germany). Cine steady state free precession images in standard long and short axes views were acquired to assess left ventricular volumes and mass. Cardiovascular risk factors (blood pressure, HDL/LDL cholesterol, smoking, body mass index) were assessed and coronary artery calcification (CAC) was quantified by electron beam computed tomography. Results Left ventricular muscle mass (mean LVMM = 140 ± 27 g; 73 ± 13 g/m²) increased with increasing left ventricular end-diastolic volume (mean LVEDV = 137 ± 32 ml; 72 ± 15ml/m²) (r = 0.41, P r = 0.33, P = 0.005) and diastolic (r = 0.28, P = 0.005) blood pressures. Left ventricular EDV increased up to the age of 55 years, but decreased thereafter. Runners with LVMM â¥150 g had significantly higher CAC scores than runners with LVMM P = 0.04). Conclusions Increases in LVMM and LVEDV may not only represent a response to exercise but are dependent on age and blood pressure, also. In addition, a left ventricular hypertrophy without an increase in volume may be an indicator for early subclinical cardiac alterations in response to risk factor exposure.
- Subjects
LEFT heart ventricle; CARDIOVASCULAR diseases risk factors; RUNNERS (Sports); CARDIAC magnetic resonance imaging; ATHEROSCLEROTIC plaque; HEART anatomy; DISEASES
- Publication
International Journal of Cardiovascular Imaging, 2009, Vol 25, Issue 1, p71
- ISSN
1569-5794
- Publication type
Article
- DOI
10.1007/s10554-008-9337-x