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- Title
Adenocarcinoma Ex-Goblet Cell Carcinoid of the Appendix With Metastatic Peritoneal Spread to Meckel's Diverticulum and Endometriosis.
- Authors
Lowenthal, Brett Matthew; Lin, Grace Y.; Tipps, Ann M. Ponsford; Hosseini, Mojgan
- Abstract
Adenocarcinoma ex-goblet cell carcinoid is a very rare and histologically unique appendiceal malignancy with dual glandular and neuroendocrine differentiation. There is a high incidence of this tumor among middle-aged women with metastasis to the gynecologic tract with the mode of metastasis following peritoneal spread rather than hematogenous distribution. Adenocarcinoma ex-goblet cell carcinoid can spread to any peritoneal site including ovaries or omentum. We report a 37-year-old healthy woman who initially presented with right lower quadrant abdominal pain and pseudomyxoma peritonei. Histopathology of the appendectomy specimen revealed an adenocarcinoma ex-goblet cell carcinoid, signet ring cell type. Follow-up right hemicolectomy, omentectomy, bilateral salpingo-oophorectomy, and regional peritoneal resections revealed metastatic involvement by adenocarcinoma ex-goblet cell carcinoid, signet ring cell type. In this report, we describe a case of appendiceal adenocarcinoma ex goblet cell carcinoid with metastases to Meckel's diverticulum and areas of pelvic endometriosis, which have not been previously reported.
- Subjects
ADENOCARCINOMA; EXFOLIATIVE cytology; CARCINOID; APPENDIX (Anatomy); MECKEL diverticulum; ENDOMETRIOSIS
- Publication
International Journal of Surgical Pathology, 2017, Vol 25, Issue 7, p623
- ISSN
1066-8969
- Publication type
Article
- DOI
10.1177/1066896917707042