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Active transport of rhodamine 123 by the human multidrug transporter P-glycoprotein involves two independent outer gates.
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- Pharmacology Research & Perspectives, 2020, v. 8, n. 2, p. 1, doi. 10.1002/prp2.572
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- Article
Structural basis of organic cation transporter-3 inhibition.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34284-8
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- Article
Structural basis of organic cation transporter-3 inhibition.
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- Nature Communications, 2022, v. 13, p. 1, doi. 10.1038/s41467-022-34284-8
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- Article
Nanopharmacological Force Sensing to Reveal Allosteric Coupling in Transporter Binding Sites.
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- Angewandte Chemie International Edition, 2016, v. 55, n. 5, p. 1719, doi. 10.1002/anie.201508755
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- Publication type:
- Article
The Bile Salt Export Pump: Molecular Structure, Study Models and Small-Molecule Drugs for the Treatment of Inherited BSEP Deficiencies.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 2, p. 784, doi. 10.3390/ijms22020784
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- Article
ABC transporters of Fasciola hepatica as putative drug targets.
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- 2011
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- Publication type:
- Abstract
LRET-based intramolecular distance measurements in LeuT<sub>Aa</sub>.
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- 2011
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- Abstract
Molecular engineering of the TRPC3 pore structure identifies Ca<sup>2+</sup> permeation through TRPC3 channels as a key determinant of cardiac calcineurin/NFAT signaling.
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- 2010
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- Abstract
Conformation of membrane-inserted P-glycoprotein.
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- 2010
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- Abstract
Regulation of the transient receptor potential channel TRPA1 by its N-terminal ankyrin repeat domain.
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- Journal of Molecular Modeling, 2013, v. 19, n. 11, p. 4689, doi. 10.1007/s00894-012-1505-1
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- Publication type:
- Article
Nanopharmacological Force Sensing to Reveal Allosteric Coupling in Transporter Binding Sites.
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- Angewandte Chemie, 2016, v. 128, n. 5, p. 1751, doi. 10.1002/ange.201508755
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- Publication type:
- Article
Ligand coupling mechanism of the human serotonin transporter differentiates substrates from inhibitors.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-023-44637-6
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- Article
Bioisosteric analogs of MDMA: Improving the pharmacological profile?
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- Journal of Neurochemistry, 2024, v. 168, n. 9, p. 2022, doi. 10.1111/jnc.16149
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- Article
Free energy profile of the substrate‐induced occlusion of the human serotonin transporter.
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- Journal of Neurochemistry, 2024, v. 168, n. 9, p. 1993, doi. 10.1111/jnc.16061
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- Publication type:
- Article
Human ABCB1 with an ABCB11-like degenerate nucleotide binding site maintains transport activity by avoiding nucleotide occlusion.
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- PLoS Genetics, 2020, v. 16, n. 10, p. 1, doi. 10.1371/journal.pgen.1009016
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- Article
Diacylglycerols interact with the L2 lipidation site in TRPC3 to induce a sensitized channel state.
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- EMBO Reports, 2022, v. 23, n. 7, p. 1, doi. 10.15252/embr.202154276
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- Article
Exploring TRPC3 Interaction with Cholesterol through Coarse-Grained Molecular Dynamics Simulations.
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- Biomolecules (2218-273X), 2022, v. 12, n. 7, p. N.PAG, doi. 10.3390/biom12070890
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- Publication type:
- Article
Characterization of DAG Binding to TRPC Channels by Target-Dependent cis–trans Isomerization of OptoDArG.
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- Biomolecules (2218-273X), 2022, v. 12, n. 6, p. 799, doi. 10.3390/biom12060799
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- Publication type:
- Article
The ABCG2 multidrug transporter is a pump gated by a valve and an extracellular lid.
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- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-13302-2
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- Article
A comparative review on the well-studied GAT1 and the understudied BGT-1 in the brain.
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- Frontiers in Physiology, 2023, p. 1, doi. 10.3389/fphys.2023.1145973
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- Article
Combined Simulation and Mutation Studies to Elucidate Selectivity of Unsubstituted Amphetamine-like Cathinones at the Dopamine Transporter.
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- Molecular Informatics, 2017, v. 36, n. 5/6, p. n/a, doi. 10.1002/minf.201600094
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- Article
Insights into binding events of GABA- and Tiagabine- analogues in the Gamma- Aminobutyric Acid Transporter 1 by means of Molecular Modelling.
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- 2012
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- Publication type:
- Abstract
The role of the degenerate nucleotide binding site in type I ABC exporters.
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- FEBS Letters, 2020, v. 594, n. 23, p. 3815, doi. 10.1002/1873-3468.13997
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- Article
Picky ABCG5/G8 and promiscuous ABCG2 ‐ a tale of fatty diets and drug toxicity.
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- FEBS Letters, 2020, v. 594, n. 23, p. 4035, doi. 10.1002/1873-3468.13938
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- Publication type:
- Article
'Second-Generation' Mephedrone Analogs, 4-MEC and 4-MePPP, Differentially Affect Monoamine Transporter Function.
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- Neuropsychopharmacology, 2015, v. 40, n. 6, p. 1321, doi. 10.1038/npp.2014.325
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- Article
Evidence for a Role of Transporter-Mediated Currents in the Depletion of Brain Serotonin Induced by Serotonin Transporter Substrates.
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- Neuropsychopharmacology, 2014, v. 39, n. 6, p. 1355, doi. 10.1038/npp.2013.331
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- Article
Conversion of chemical to mechanical energy by the nucleotide binding domains of ABCB1.
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- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-59403-7
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- Article
Unveiling the crucial role of betaine: modulation of GABA homeostasis via SLC6A1 transporter (GAT1).
- Published in:
- Cellular & Molecular Life Sciences, 2024, v. 81, n. 1, p. 1, doi. 10.1007/s00018-024-05309-w
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- Article
Lanthanide resonance energy transfer‐based distance measurements in the mammalian glutamate transporter excitatory amino acid transporter 3 (1064.12).
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- FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.1064.12
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- Publication type:
- Article
Data-driven homology modelling of P-glycoprotein in the ATP-bound state indicates flexibility of the transmembrane domains.
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- FEBS Journal, 2009, v. 276, n. 4, p. 964, doi. 10.1111/j.1742-4658.2008.06832.x
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- Publication type:
- Article
Refinement of the Central Steps of Substrate Transport by the Aspartate Transporter GltPh: Elucidating the Role of the Na2 Sodium Binding Site.
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- PLoS Computational Biology, 2015, v. 11, n. 10, p. 1, doi. 10.1371/journal.pcbi.1004551
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- Article
Mutational Analysis of the High-Affinity Zinc Binding Site Validates a Refined Human Dopamine Transporter Homology Model.
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- PLoS Computational Biology, 2013, v. 9, n. 2, p. 1, doi. 10.1371/journal.pcbi.1002909
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- Publication type:
- Article
Symmetric Allosteric Mechanism of Hexameric Escherichia coli Arginine Repressor Exploits Competition between L-Arginine Ligands and Resident Arginine Residues.
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- PLoS Computational Biology, 2010, v. 6, n. 6, p. 1, doi. 10.1371/journal.pcbi.1000801
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- Article
A Single Mutation is Sufficient to Modify the Metal Selectivity and Specificity of a Eukaryotic Manganese Superoxide Dismutase to Encompass Iron.
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- Chemistry - A European Journal, 2018, v. 24, n. 20, p. 5303, doi. 10.1002/chem.201704655
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- Article
Direct PIP<sub>2</sub> binding mediates stable oligomer formation of the serotonin transporter.
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- Nature Communications, 2017, v. 8, n. 1, p. 14089, doi. 10.1038/ncomms14089
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- Article
The Amino Terminus of LeuT Changes Conformation in an Environment Sensitive Manner.
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- Neurochemical Research, 2020, v. 45, n. 6, p. 1387, doi. 10.1007/s11064-019-02928-9
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- Article
SLC6 transporter oligomerization.
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- Journal of Neurochemistry, 2021, v. 157, n. 4, p. 919, doi. 10.1111/jnc.15145
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- Publication type:
- Article
Enantioselectivity of epoxide hydrolase catalysed oxirane ring opening: a 3D QSAR Study.
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- Journal of Computer-Aided Molecular Design, 2003, v. 17, n. 1, p. 1, doi. 10.1023/A:1024562326498
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- Article
Nucleotide binding is the critical regulator of ABCG2 conformational transitions.
- Published in:
- eLife, 2023, p. 1, doi. 10.7554/eLife.83976
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- Article
Saturation transfer difference NMR on the integral trimeric membrane transport protein GltPh determines cooperative substrate binding.
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- Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-73443-z
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- Article
Investigating the dynamic nature of the ABC transporters: ABCB1 and MsbA as examples for the potential synergies of MD theory and EPR applications.
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- Biochemical Society Transactions, 2015, v. 43, n. 5, p. 1023, doi. 10.1042/BST20150138
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- Article
Insights into the molecular evolution of oxytocin receptor ligand binding.
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- Biochemical Society Transactions, 2013, v. 41, n. 1, p. 197, doi. 10.1042/BST20120256
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- Publication type:
- Article
The Environment Shapes the Inner Vestibule of LeuT.
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- PLoS Computational Biology, 2016, v. 12, n. 11, p. 1, doi. 10.1371/journal.pcbi.1005197
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- Publication type:
- Article
Sodium Binding Stabilizes the Outward-Open State of SERT by Limiting Bundle Domain Motions.
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- Cells (2073-4409), 2022, v. 11, n. 2, p. 255, doi. 10.3390/cells11020255
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- Publication type:
- Article
Investigating the Mechanism of Sodium Binding to SERT Using Direct Simulations.
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- Frontiers in Cellular Neuroscience, 2021, v. 15, p. N.PAG, doi. 10.3389/fncel.2021.673782
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- Publication type:
- Article
Phosphatidylinositol 4,5-bisphosphate (PIP<sub>2</sub>) facilitates norepinephrine transporter dimerization and modulates substrate efflux.
- Published in:
- Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-04210-1
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- Article
Probing binding and occlusion of substrate in the human creatine transporter‐1 by computation and mutagenesis.
- Published in:
- Protein Science: A Publication of the Protein Society, 2024, v. 33, n. 1, p. 1, doi. 10.1002/pro.4842
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- Article
Dopamine transporter oligomerization involves the scaffold domain, but spares the bundle domain.
- Published in:
- PLoS Computational Biology, 2018, v. 14, n. 6, p. 1, doi. 10.1371/journal.pcbi.1006229
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- Publication type:
- Article