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- Title
Analytical performance of commercially-available assays for feline insulin-like growth factor 1 (IGF-1), adiponectin and ghrelin measurements.
- Authors
Tvarijonaviciute, Asta; German, Alexander J; Martínez-Subiela, Silvia; Tecles, Fernando; Ceron, Jose J
- Abstract
The objective of this study was to evaluate three commercially-available human assays for the determination of adiponectin, ghrelin and insulin-like growth factor 1 (IGF-1) concentrations in feline serum samples. Intra- and interassay coefficients of variation were lower than 20%, 15% and 6% for adiponectin, ghrelin and IGF-1 assays, respectively. Dilutions of feline serum pools resulted in linear regression equations in all kits. Mean recovery of adiponectin, ghrelin and IGF-1 assays were 107%, 102% and 105%, respectively. Significant differences were detected in adiponectin and ghrelin concentrations between lean and obese cats (P <0.05 in both cases), but there was no difference in IGF-1 concentrations (P = 0.12).
- Publication
Journal of Feline Medicine & Surgery, 2012, Vol 14, Issue 2, p138
- ISSN
1098-612X
- Publication type
Article
- DOI
10.1177/1098612X11432236