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- Title
Association of diabetes therapy-related quality of life and physical activity levels in patients with type 2 diabetes receiving medication therapy: the Diabetes Distress and Care Registry at Tenri (DDCRT 17).
- Authors
Hayashino, Yasuaki; Tsujii, Satoru; Ishii, Hitoshi; for the Diabetes Distress and Care Registry at Tenri Study Group
- Abstract
Aim: To examine the association between diabetes therapy-related quality of life (DTR-QOL) and physical activity levels, and identify factors associated with high diabetes therapy-related quality of life. Methods: Cross-sectional data from 2970 patients with type 2 diabetes in a Japanese diabetes registry were assessed for independent correlations between DTR-QOL (domains 1–4) and high physical activity levels. Data collected by the International Physical Activity Questionnaire were analyzed by logistic regression and adjusted for potential confounders.Results: The mean patient age, BMI and HbA1c level were 65.8 years, 24.7 kg/m2 and 7.6% (58.7 mmol/mol), respectively. Univariate analysis showed that DTR-QOL domain 1, 2 and 4 scores were significantly associated with physical activity levels (<italic>p</italic> = 0.0046, <italic>p</italic> = 0.0004 and <italic>p</italic> < 0.001, respectively, but domain 3 score was not (<italic>p</italic> = 0.5073). In a multivariable-adjusted logistic regression model, odds ratios (ORs) of DTR-QOL domains 1, 3 and 4 were independently associated with high physical activity (ORs for 2nd to 4th quartile and <italic>p</italic> for trend; [domain 1] 1.16, 1.56, 1.22, <italic>p</italic> = 0.032; [domain 3] 1.45, 1.55, 1.38, <italic>p</italic> = 0.049; [domain 4] 1.09, 1.30, 1.51, <italic>p</italic> = 0.001, respectively), but domain 2 was not (ORs for 2nd to 4th quartile and <italic>p</italic> for trend; 1.19, 1.26, 1.23, <italic>p</italic> = 0.096).Conclusion: High diabetes therapy-related QOL scores were associated with high levels of physical activity in patients with type 2 diabetes. Because this is a cross-sectional study, further study is needed to evaluate the causal association between therapy-related QOL and physical activity.
- Subjects
ENDOPLASMIC reticulum; ORGANELLES; PEROXIREDOXINS; NEURODEGENERATION; AUTOPHAGY
- Publication
Acta Diabetologica, 2018, Vol 55, Issue 2, p165
- ISSN
0940-5429
- Publication type
Article
- DOI
10.1007/s00592-017-1080-0