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Biological techniques: Edit the genome to understand it.
Published in:
Nature, 2014, v. 513, n. 7516, p. 40, doi. 10.1038/nature13659
By:
- Urnov, Fyodor D.
Publication type:
Article
Designed transcription factors as structural, functional and therapeutic probes of chromatin in vivo.
Published in:
EMBO Reports, 2002, v. 3, n. 7, p. 610, doi. 10.1093/embo-reports/kvf140
By:
- Urnov, Fyodor D.;
- Rebar, Edward J.;
- Reik, Andreas;
- Pandolfi, Pier Paolo
Publication type:
Article
Engineering CRISPR Cures: An Interview with Fyodor Urnov.
Published in:
2023
By:
- Urnov, Fyodor D.;
- Grinstein, Jonathan D.
Publication type:
Interview
Genome editing with engineered zinc finger nucleases.
Published in:
2010
By:
- Urnov, Fyodor D.;
- Rebar, Edward J.;
- Holmes, Michael C.;
- Zhang, H. Steve;
- Gregory, Philip D.
Publication type:
journal article
1003. Targeted Site-Specific Integration in Human Cells Using Designed Zinc Finger Nucleases.
Published in:
Molecular Therapy, 2006, v. 13, p. S386, doi. 10.1016/j.ymthe.2006.08.1097
By:
- Urnov, Fyodor D.;
- Lombardo, Angelo;
- Rock, Jeremy;
- Moehle, Erica;
- Miller, Jeffrey C.;
- Ya-Li Lee;
- Gregory, Philip D.;
- Naldini, Luigi;
- Holmes, Michael C.
Publication type:
Article
1040. Towards Gene Correction Therapy for Wiskott-Aldrich Syndrome Using Designed Zinc Finger Endonucleases.
Published in:
Molecular Therapy, 2006, v. 13, p. S398, doi. 10.1016/j.ymthe.2006.08.1136
By:
- Davis, Brian R.;
- Prokopishyn, Nicole L.;
- Rosenberg, Jonathan;
- DiCola, Michael;
- Brosius, Jennifer;
- Michael Blaese, R.;
- Metz, Richard A.;
- Zhang, Lei;
- Xia, Danny;
- Miller, Jeffrey C.;
- Kim, Kenneth;
- Urnov, Fyodor D.;
- Gregory, Philip D.;
- Holmes, Michael C.
Publication type:
Article
555. Large-Scale, Flow-Based Electroporation To Deliver Engineered Zinc Finger Protein Nucleases That Mediate High-Efficiency Disruption of the Human CCR5 Gene.
Published in:
Molecular Therapy, 2006, v. 13, p. S214, doi. 10.1016/j.ymthe.2006.08.627
By:
- Holmes, Michael C.;
- Liu, Linda;
- Perez, Elena;
- Linhong Li;
- Shivakumar, Rama;
- Allen, Cornell;
- Olga Liu;
- Miller, Jeffrey C.;
- Urnov, Fyodor D.;
- Kim, Kenneth;
- Rebar, Edward J.;
- Ando, Dale;
- Gregory, Philip D.;
- Riley, James;
- Peshwa, Madhusudan;
- June, Carl
Publication type:
Article
738. Towards Gene Correction of X-Linked SCID Using Engineered Zinc Finger Nucleases and Integrase Defective Lentiviral Delivery<sup>*</sup>.
Published in:
Molecular Therapy, 2006, v. 13, p. S285, doi. 10.1016/j.ymthe.2006.08.819
By:
- Lombardo, Angelo;
- Beausejour, Christian;
- Urnov, Fyodor D.;
- Miller, Jeffrey C.;
- Aiuti, Alessandro;
- Gregory, Philip D.;
- Holmes, Michael C.;
- Naldini, Luigi
Publication type:
Article
974. Towards Gene Knock out Therapy for AIDS/HIV: Targeted Disruption of CCR5 Using Engineered Zinc Finger Protein Nucleases (ZFNs)
Published in:
2005
By:
- Jouvenot, Yann;
- Perez, Elena;
- Urnov, Fyodor D.;
- Beausejour, Christian;
- Rock, Jeremy;
- Lee, Ya-Li;
- Miller, Jeffrey C.;
- Rebar, Edward J.;
- Holmes, Michael C.;
- Ando, Dale;
- Riley, Jim;
- Gregory, Philip D.;
- June, Carl
Publication type:
Abstract
379. New Zinc Finger Protein Nuclease Architectures for More Efficient Gene Modification Therapies
Published in:
2005
By:
- Miller, Jeffrey C.;
- Zhang, Lei;
- Urnov, Fyodor D.;
- Patterson, Sarah;
- Xia, Danny;
- Rock, Jeremy;
- Augustus, Sheldon;
- Pabo, Carl O.;
- Gregory, Philip D.;
- Rebar, Edward J.;
- Holmes, Michael C.
Publication type:
Abstract
346. Gene Correction of X-Linked SCID Using Engineered Zinc Finger Nucleases and Integration Defective Lentiviral Delivery
Published in:
2005
By:
- Lombardo, Angelo;
- Beausejour, Christian;
- Urnov, Fyodor D.;
- Miller, Jeffrey C.;
- Holmes, Michael C.;
- Gregory, Philip D.;
- Naldini, Luigi
Publication type:
Abstract
337. Towards Gene Correction Therapy for Wiskott-Aldrich Syndrome with Engineered Zinc Finger Nucleases
Published in:
2005
By:
- Zhang, Lei;
- Urnov, Fyodor D.;
- Miller, Jeffrey C.;
- Beausejour, Christian;
- Lee, Ya-Li;
- Rock, Jeremy;
- Kim, Kenneth;
- Holmes, Michael C.;
- Gregory, Philip D.
Publication type:
Abstract
85. Development of Zinc Finger Nucleases for Therapeutic Gene Correction of Sickle Cell Anemia
Published in:
2005
By:
- Miller, Jeffrey C.;
- Urnov, Fyodor D.;
- Lee, Ya-li;
- Rock, Jeremy;
- Sorba, Tyler;
- Patterson, Sarah;
- Gregory, Philip D.;
- Holmes, Michael C.;
- Rebar, Edward J.
Publication type:
Abstract
Activation domains for controlling plant gene expression using designed transcription factors.
Published in:
Plant Biotechnology Journal, 2013, v. 11, n. 6, p. 671, doi. 10.1111/pbi.12057
By:
- Li, Jianquan;
- Blue, Ryan;
- Zeitler, Bryan;
- Strange, Tonya L.;
- Pearl, Jocelynn R.;
- Huizinga, David H.;
- Evans, Steve;
- Gregory, Philip D.;
- Urnov, Fyodor D.;
- Petolino, Joseph F.
Publication type:
Article
Transcriptional activation of Brassica napusβ-ketoacyl-ACP synthase II with an engineered zinc finger protein transcription factor.
Published in:
Plant Biotechnology Journal, 2012, v. 10, n. 7, p. 783, doi. 10.1111/j.1467-7652.2012.00695.x
By:
- Gupta, Manju;
- DeKelver, Russell C.;
- Palta, Asha;
- Clifford, Carla;
- Gopalan, Sunita;
- Miller, Jeffrey C.;
- Novak, Stephen;
- Desloover, Daniel;
- Gachotte, Daniel;
- Connell, James;
- Flook, Josh;
- Patterson, Thomas;
- Robbins, Kelly;
- Rebar, Edward J.;
- Gregory, Philip D.;
- Urnov, Fyodor D.;
- Petolino, Joseph F.
Publication type:
Article
Targeting of N-CoR and histone deacetylase 3 by the oncoprotein v-ErbA yields a chromatin infrastructure-dependent transcriptional repression pathway.
Published in:
EMBO Journal, 2000, v. 19, n. 15, p. 4074, doi. 10.1093/emboj/19.15.4074
By:
- Urnov, Fyodor D.;
- Yee, Janet;
- Sachs, Laurent;
- Collingwood, Trevor N.;
- Bauer, Anton;
- Beug, Hartmut;
- Shi, Yun-Bo;
- Wolffe, Alan P.
Publication type:
Article
Chromatin remodeling as a guide to transcriptional regulatory networks in mammals.
Published in:
Journal of Cellular Biochemistry, 2003, v. 88, n. 4, p. 684, doi. 10.1002/jcb.10397
By:
- Urnov, Fyodor D.
Publication type:
Article
In vivo cleavage of transgene donors promotes nuclease-mediated targeted integration.
Published in:
Biotechnology & Bioengineering, 2013, v. 110, n. 3, p. 871, doi. 10.1002/bit.24733
By:
- Cristea, Sandra;
- Freyvert, Yevgeniy;
- Santiago, Yolanda;
- Holmes, Michael C.;
- Urnov, Fyodor D.;
- Gregory, Philip D.;
- Cost, Gregory J.
Publication type:
Article
Robotic RNA extraction for SARS-CoV-2 surveillance using saliva samples.
Published in:
PLoS ONE, 2021, v. 16, n. 8, p. 1, doi. 10.1371/journal.pone.0255690
By:
- Hamilton, Jennifer R.;
- Stahl, Elizabeth C.;
- Tsuchida, Connor A.;
- Lin-Shiao, Enrique;
- Tsui, C. Kimberly;
- Pestal, Kathleen;
- Gildea, Holly K.;
- Witkowsky, Lea B.;
- Moehle, Erica A.;
- McDevitt, Shana L.;
- McElroy, Matthew;
- Keller, Amanda;
- Sylvain, Iman;
- Hirsh, Ariana;
- Ciling, Alison;
- Ehrenberg, Alexander J.;
- Ringeisen, Bradley R.;
- Huberty, Garth;
- Urnov, Fyodor D.;
- Giannikopoulos, Petros
Publication type:
Article
p300 stimulates transcription instigated by ligand-bound thyroid hormone receptor at a step subsequent to chromatin disruption.
Published in:
EMBO Journal, 1999, v. 18, n. 20, p. 5634, doi. 10.1093/emboj/18.20.5634
By:
- Li, Qiao;
- Imhof, Axel;
- Collingwood, Trevor N.;
- Urnov, Fyodor D.;
- Wolffe, Alan P.
Publication type:
Article
Piloting an integrated SARS-CoV-2 testing and data system for outbreak containment among college students: A prospective cohort study.
Published in:
PLoS ONE, 2021, v. 16, n. 1, p. 1, doi. 10.1371/journal.pone.0245765
By:
- Packel, Laura;
- Reingold, Arthur;
- Hunter, Lauren;
- Facente, Shelley;
- Li, Yi;
- Harte, Anna;
- Nicolette, Guy;
- Urnov, Fyodor D.;
- Lu, Michael;
- Petersen, Maya
Publication type:
Article
A feel for the template: zinc finger protein transcription factors and chromatin.
Published in:
Biochemistry & Cell Biology, 2002, v. 80, n. 3, p. 321, doi. 10.1139/o02-084
By:
- Urnov, Fyodor D
Publication type:
Article
Chromatin as a Tool for the Study of Genome Function in Cancer.
Published in:
Annals of the New York Academy of Sciences, 2003, v. 983, n. 1, p. 5, doi. 10.1111/j.1749-6632.2003.tb05958.x
By:
- URNOV, FYODOR D.
Publication type:
Article
Translating dosage compensation to trisomy 21.
Published in:
Nature, 2013, v. 500, n. 7462, p. 296, doi. 10.1038/nature12394
By:
- Jiang, Jun;
- Jing, Yuanchun;
- Cost, Gregory J.;
- Chiang, Jen-Chieh;
- Kolpa, Heather J.;
- Cotton, Allison M.;
- Carone, Dawn M.;
- Carone, Benjamin R.;
- Shivak, David A.;
- Guschin, Dmitry Y.;
- Pearl, Jocelynn R.;
- Rebar, Edward J.;
- Byron, Meg;
- Gregory, Philip D.;
- Brown, Carolyn J.;
- Urnov, Fyodor D.;
- Hall, Lisa L.;
- Lawrence, Jeanne B.
Publication type:
Article
Dissection of Splicing Regulation at an Endogenous Locus by Zinc-Finger Nuclease-Mediated Gene Editing.
Published in:
PLoS ONE, 2011, v. 6, n. 2, p. 1, doi. 10.1371/journal.pone.0016961
By:
- Cristea, Sandra;
- Gregory, Philip D.;
- Urnov, Fyodor D.;
- Cost, Gregory J.
Publication type:
Article
A call for science-based review of the European court's decision on gene-edited crops.
Published in:
2018
By:
- Urnov, Fyodor D;
- Ronald, Pamela C;
- Carroll, Dana
Publication type:
Letter
A call for science-based review of the European court's decision on gene-edited crops.
Published in:
2018
By:
- Urnov, Fyodor D;
- Ronald, Pamela C;
- Carroll, Dana
Publication type:
Letter
Improved specificity of TALE-based genome editing using an expanded RVD repertoire.
Published in:
Nature Methods, 2015, v. 12, n. 5, p. 465, doi. 10.1038/nmeth.3330
By:
- Miller, Jeffrey C;
- Zhang, Lei;
- Xia, Danny F;
- Campo, John J;
- Ankoudinova, Irina V;
- Guschin, Dmitry Y;
- Babiarz, Joshua E;
- Meng, Xiangdong;
- Hinkley, Sarah J;
- Lam, Stephen C;
- Paschon, David E;
- Vincent, Anna I;
- Dulay, Gladys P;
- Barlow, Kyle A;
- Shivak, David A;
- Leung, Elo;
- Kim, Jinwon D;
- Amora, Rainier;
- Urnov, Fyodor D;
- Gregory, Philip D
Publication type:
Article
Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases.
Published in:
Nature Methods, 2012, v. 9, n. 10, p. 993, doi. 10.1038/nmeth.2143
By:
- Straimer, Judith;
- Lee, Marcus C S;
- Lee, Andrew H;
- Zeitler, Bryan;
- Williams, April E;
- Pearl, Jocelynn R;
- Zhang, Lei;
- Rebar, Edward J;
- Gregory, Philip D;
- Llinás, Manuel;
- Urnov, Fyodor D;
- Fidock, David A
Publication type:
Article
Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures.
Published in:
Nature Methods, 2011, v. 8, n. 1, p. 74, doi. 10.1038/nmeth.1539
By:
- Doyon, Yannick;
- Vo, Thuy D.;
- Mendel, Matthew C.;
- Greenberg, Shon G.;
- Jianbin Wang;
- Xia, Danny F.;
- Miller, Jeffrey C.;
- Urnov, Fyodor D.;
- Gregory, Philip D.;
- Holmes, Michael C.
Publication type:
Article
Rapid and efficient clathrin-mediated endocytosis revealed in genome-edited mammalian cells.
Published in:
Nature Cell Biology, 2011, v. 13, n. 3, p. 331, doi. 10.1038/ncb2175
By:
- Doyon, Jeffrey B.;
- Zeitler, Bryan;
- Cheng, Jackie;
- Cheng, Aaron T.;
- Cherone, Jennifer M.;
- Santiago, Yolanda;
- Lee, Andrew H.;
- Vo, Thuy D.;
- Doyon, Yannick;
- Miller, Jeffrey C.;
- Paschon, David E.;
- Lei Zhang;
- Rebar, Edward J.;
- Gregory, Philip D.;
- Urnov, Fyodor D.;
- Drubin, David G.
Publication type:
Article
Identification of chromosome sequence motifs that mediate meiotic pairing and synapsis in C. elegans.
Published in:
2009
By:
- Phillips, Carolyn M.;
- Meng, Xiangdong;
- Zhang, Lei;
- Chretien, Jacqueline H.;
- Urnov, Fyodor D.;
- Dernburg, Abby F.
Publication type:
Correction notice
Identification of chromosome sequence motifs that mediate meiotic pairing and synapsis in C. elegans.
Published in:
Nature Cell Biology, 2009, v. 11, n. 8, p. 934, doi. 10.1038/ncb1904
By:
- Phillips, Carolyn M.;
- Xiangdong Meng;
- Lei Zhang;
- Chretien, Jacqueline H.;
- Urnov, Fyodor D.;
- Dernburg, Abby F.
Publication type:
Article
Chromatin remodeling and transcriptional activation: the cast (in order of appearance).
Published in:
Oncogene, 2001, v. 20, n. 24, p. 2991, doi. 10.1038/sj.onc.1204323
By:
- Urnov, Fyodor D;
- Wolffe, Alan P
Publication type:
Article
Highly efficient endogenous human gene correction using designed zinc-finger nucleases.
Published in:
Nature, 2005, v. 435, n. 7042, p. 646, doi. 10.1038/nature03556
By:
- Urnov, Fyodor D.;
- Miller, Jeffrey C.;
- Lee, Ya-Li;
- Beausejour, Christian M.;
- Rock, Jeremy M.;
- Augustus, Sheldon;
- Jamieson, Andrew C.;
- Porteus, Matthew H.;
- Gregory, Philip D.;
- Holmes, Michael C.
Publication type:
Article
Zinc-finger nuclease-driven targeted integration into mammalian genomes using donors with limited chromosomal homology.
Published in:
Nucleic Acids Research, 2010, v. 38, n. 15, p. e152, doi. 10.1093/nar/gkq512
By:
- Orlando, Salvatore J.;
- Santiago, Yolanda;
- DeKelver, Russell C.;
- Freyvert, Yevgeniy;
- Boydston, Elizabeth A.;
- Moehle, Erica A.;
- Choi, Vivian M.;
- Gopalan, Sunita M.;
- Lou, Jacqueline F.;
- Li, James;
- Miller, Jeffrey C.;
- Holmes, Michael C.;
- Gregory, Philip D.;
- Urnov, Fyodor D.;
- Cost, Gregory J.
Publication type:
Article
Genetic engineering of human pluripotent cells using TALE nucleases.
Published in:
Nature Biotechnology, 2011, v. 29, n. 8, p. 731, doi. 10.1038/nbt.1927
By:
- Hockemeyer, Dirk;
- Wang, Haoyi;
- Kiani, Samira;
- Lai, Christine S;
- Gao, Qing;
- Cassady, John P;
- Cost, Gregory J;
- Zhang, Lei;
- Santiago, Yolanda;
- Miller, Jeffrey C;
- Zeitler, Bryan;
- Cherone, Jennifer M;
- Meng, Xiangdong;
- Hinkley, Sarah J;
- Rebar, Edward J;
- Gregory, Philip D;
- Urnov, Fyodor D;
- Jaenisch, Rudolf
Publication type:
Article
A TALE nuclease architecture for efficient genome editing.
Published in:
Nature Biotechnology, 2011, v. 29, n. 2, p. 143, doi. 10.1038/nbt.1755
By:
- Miller, Jeffrey C.;
- Siyuan Tan;
- Guijuan Qiao;
- Barlow, Kyle A.;
- Jianbin Wang;
- Xia, Danny F.;
- Xiangdong Meng;
- Paschon, David E.;
- Elo Leung;
- Hinkley, Sarah J.;
- Dulay, Gladys P.;
- Hua, Kevin L.;
- Ankoudinova, Irina;
- Cost, Gregory J.;
- Urnov, Fyodor D.;
- Zhang, H. Steve;
- Holmes, Michael C.;
- Lei Zhang;
- Gregory, Philip D.;
- Rebar, Edward J.
Publication type:
Article
Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases.
Published in:
Nature Biotechnology, 2009, v. 27, n. 9, p. 851, doi. 10.1038/nbt.1562
By:
- Hockemeyer, Dirk;
- Soldner, Frank;
- Beard, Caroline;
- Qing Gao;
- Mitalipova, Maisam;
- DeKelver, Russell C.;
- Katibah, George E.;
- Amora, Ranier;
- Boydston, Elizabeth A.;
- Zeitler, Bryan;
- Xiangdong Meng;
- Miller, Jeffrey C.;
- Lei Zhang;
- Rebar, Edward J.;
- Gregory, Philip D.;
- Urnov, Fyodor D.;
- Jaenisch, Rudolf
Publication type:
Article
Establishment of HIV-1 resistance in CD4<sup>+</sup> T cells by genome editing using zinc-finger nucleases.
Published in:
Nature Biotechnology, 2008, v. 26, n. 7, p. 808, doi. 10.1038/nbt1410
By:
- Perez, Elena E;
- Wang, Jianbin;
- Miller, Jeffrey C;
- Jouvenot, Yann;
- Kim, Kenneth A;
- Liu, Olga;
- Wang, Nathaniel;
- Lee, Gary;
- Bartsevich, Victor V;
- Lee, Ya-Li;
- Guschin, Dmitry Y;
- Rupniewski, Igor;
- Waite, Adam J;
- Carpenito, Carmine;
- Carroll, Richard G;
- S Orange, Jordan;
- Urnov, Fyodor D;
- Rebar, Edward J;
- Ando, Dale;
- Gregory, Philip D
Publication type:
Article
Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases.
Published in:
Nature Biotechnology, 2008, v. 26, n. 6, p. 702, doi. 10.1038/nbt1409
By:
- Doyon, Yannick;
- McCammon, Jasmine M;
- Miller, Jeffrey C;
- Faraji, Farhoud;
- Ngo, Catherine;
- Katibah, George E;
- Amora, Rainier;
- Hocking, Toby D;
- Zhang, Lei;
- Rebar, Edward J;
- Gregory, Philip D;
- Urnov, Fyodor D;
- Amacher, Sharon L
Publication type:
Article
Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery.
Published in:
Nature Biotechnology, 2007, v. 25, n. 11, p. 1298, doi. 10.1038/nbt1353
By:
- Lombardo, Angelo;
- Genovese, Pietro;
- Beausejour, Christian M.;
- Colleoni, Silvia;
- Ya-Li Lee;
- Kim, Kenneth A.;
- Ando, Dale;
- Urnov, Fyodor D.;
- Galli, Cesare;
- Gregory, Philip D.;
- Holmes, Michael C.;
- Naldini, Luigi
Publication type:
Article
Mammalian interspecies substitution of immune modulatory alleles by genome editing.
Published in:
Scientific Reports, 2016, p. 21645, doi. 10.1038/srep21645
By:
- Lillico, Simon G.;
- Proudfoot, Chris;
- King, Tim J.;
- Tan, Wenfang;
- Zhang, Lei;
- Mardjuki, Rachel;
- Paschon, David E.;
- Rebar, Edward J.;
- Urnov, Fyodor D.;
- Mileham, Alan J.;
- McLaren, David G.;
- Whitelaw, C. Bruce A.
Publication type:
Article

Found: 43