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- Title
Ultrafast 1D MR thermometry using phase or frequency mapping.
- Authors
Mei, Chang-Sheng; Mulkern, Robert; Oshio, Koichi; Chen, Nan-kuei; Madore, Bruno; Panych, Lawrence; Hynynen, Kullervo; McDannold, Nathan
- Abstract
Object: To develop an ultrafast MRI-based temperature monitoring method for application during rapid ultrasound exposures in moving organs. Materials and methods: A slice selective 90° − 180° pair of RF pulses was used to solicit an echo from a column, which was then sampled with a train of gradient echoes. In a gel phantom, phase changes of each echo were compared to standard gradient-echo thermometry, and temperature monitoring was tested during focused ultrasound sonications. Signal-to-noise ratio (SNR) performance was evaluated in vivo in a rabbit brain, and feasibility was tested in a human heart. Results: The correlation between each echo in the acquisition and MRI-based temperature measurements was good ( R = 0.98 ± 0.03). A temperature sampling rate of 19 Hz was achieved at 3T in the gel phantom. It was possible to acquire the water frequency in the beating heart muscle with 5-Hz sampling rate during a breath hold. Conclusion: Ultrafast thermometry via phase or frequency monitoring along single columns was demonstrated. With a temporal resolution around 50 ms, it may be possible to monitor focal heating produced by short ultrasound pulses.
- Subjects
MEDICAL imaging systems; MAGNETIC resonance imaging; PROTON magnetic resonance spectroscopy; MEDICAL thermometry; TEMPERATURE measurements; PHASE transitions
- Publication
MAGMA: Magnetic Resonance Materials in Physics, Biology & Medicine, 2012, Vol 25, Issue 1, p5
- ISSN
0968-5243
- Publication type
Article
- DOI
10.1007/s10334-011-0272-9