We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Synthesis and Antiviral Activity of Copolymers of Hydroxycinnamic Acid with N-Vinylamides.
- Authors
Nesterova, N. A.; Shtro, A. A.; Panarin, E. F.
- Abstract
Radical copolymerization of coumarin with N-vinylamides (N‑vinylpyrrolidone, N-methyl-N-vinylacetamide, N-vinylformamide) has been used to prepare copolymers of various composition with variable molecular weights. Subsequent reactions in their polymer chains affords water-soluble copolymers of salts of hydroxycinnamic acid and its hydrazides. The synthesized copolymers of hydroxycinnamic acid salts and hydrazides with N-vinylamides have low cytotoxicity and demonstrate the pronounced antiviral activity against human respiratory syncytial virus (strain A2).
- Subjects
HYDROXYCINNAMIC acids; COPOLYMERS; RESPIRATORY syncytial virus; CYTOTOXINS; HYDRAZIDES; COPOLYMERIZATION
- Publication
Doklady Chemistry, 2023, Vol 513, Issue 2, p389
- ISSN
0012-5008
- Publication type
Article
- DOI
10.1134/S0012500823600992