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- Title
Dyslipidemia and its components across body weight categories among type II diabetic patients in the west of Iran.
- Authors
Izadi, Neda; Najafi, Farid; Hashemi Nazari, Seyed Saeed; Rahimi, Mer Ali; Shetabi, Hamid Reza
- Abstract
Introduction: The combination of dyslipidemia, obesity, and hyperglycemia can accelerate the progression to CVD. Therefore, this study aims to investigate dyslipidemia and its components across body weight categories among type II diabetic patients. Methods: The data for this cross-sectional study was extracted from the records of diabetic patients during 2014-15. Dyslipidemia was defined based on the NCEP/ATP III classification of lipid profile. In addition, restricted cubic spline method was used to evaluate a potential nonlinear relationship between BMI and dyslipidemia, and its components. Results: The median age of 1977 patients was 55 (IQR=14) years. 61.11% was females. The prevalence of dyslipidemia was 91.29% (95% CI: 90.05-92.54). Being an overweight diabetic patient was associated with an increased risk of dyslipidemia (OR=1.87-2.78), hypertriglyceridemia (OR=1.64; 95% CI: 1.29-2.09) and hypo-HDL (OR=1.55; 95% CI: 1.20- 2.01). Similarly, obesity also increased the risk of dyslipidemia (OR=1.94; 95% CI: 1.28-2.95), hypertriglyceridemia (OR=1.66; 95% CI: 1.29-2.12) and hypo-HDL (OR=1.86; 95% CI: 1.41- 2.43). The non-linear dose-response relationship was associated with a significant increase then decrease in the risk of dyslipidemia, hypertriglyceridemia, and hypo-HDL in men and women as per 1 kg/m2 increase in BMI. Conclusion: With regards to the result, we know that there is no linear relationship between lipid profiles and BMI, the bell-shape association between dyslipidemia, hypertriglyceridemia, and hypo-HDL need to be further investigated in both diabetic and general population in men and women separately. In addition, for public health section, an appropriate intervention is of most important priorities.
- Subjects
IRAN; CONFERENCES &; conventions; HYPERLIPIDEMIA; TYPE 2 diabetes; OBESITY; BODY mass index; DISEASE risk factors
- Publication
Journal of Safety Promotion & Injury Prevention, 2019, Vol 7, Issue 3, p281
- ISSN
2345-2455
- Publication type
Article