We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
The subtelomeric region is important for chromosome recognition and pairing during meiosis.
- Authors
Calderón, María del Carmen; Rey, María-Dolores; Cabrera, Adoración; Prieto, Pilar
- Abstract
The process of meiosis results in the formation of haploid daughter cells, each of which inherit a half of the diploid parental cells' genetic material. The ordered association of homologues (identical chromosomes) is a critical prerequisite for a successful outcome of meiosis. Homologue recognition and pairing are initiated at the chromosome ends, which comprise the telomere dominated by generic repetitive sequences, and the adjacent subtelomeric region, which harbours chromosome-specific sequences. In many organisms telomeres are responsible for bringing the ends of the chromosomes close together during early meiosis, but little is known regarding the role of the subtelomeric region sequence during meiosis. Here, the observation of homologue pairing between a pair ofHordeum chilense chromosomes lacking the subtelomeric region on one chromosome arm indicates that the subtelomeric region is important for the process of homologous chromosome recognition and pairing.
- Subjects
MEIOSIS; HOMOLOGOUS chromosomes; HAPLOIDY; TELOMERES; NUCLEOTIDE sequence
- Publication
Scientific Reports, 2014, p1
- ISSN
2045-2322
- Publication type
Article
- DOI
10.1038/srep06488