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- Title
A retrospective analysis of the concordance of in‐house fungal culture and a commercial quantitative PCR from 16 dermatology referral practices across the USA (2018–2019).
- Authors
Frost, Katrina; Schick, Anthea; Mount, Rebecca
- Abstract
QPCR sensitivity and specificity for the initial diagnosis of dermatophytosis and for treatment monitoring were 72.4% (95%CI 59.1-83.3) and 98.7% (95%CI 97.3-99.5), and 77.8% (95%CI 57.7-91.4) and 92.0% (95%CI 80.1-97.8), respectively. The analytical sensitivity of the dermatophyte qPCR assays is determined by the minimum amount of dermatophyte DNA that is above the limit of detection.15 Although qPCR is a highly sensitive diagnostic test, given the number of false negatives in the current study, it may be possible that the analytical sensitivity of the dermatophyte qPCR assays is actually lower than reported previously. There were 590 paired qPCR and in-house fungal cultures used for the initial diagnosis of dermatophytosis (Table 3). B Background b - Commercial quantitative (q)PCR and fungal culture can be used concurrently or individually to test for dermatophytosis with a reported high sensitivity and specificity.
- Subjects
FUNGAL cultures; CAT diseases; DERMATOLOGY; RETROSPECTIVE studies; ANIMAL welfare
- Publication
Veterinary Dermatology, 2022, Vol 33, Issue 5, p392
- ISSN
0959-4493
- Publication type
Article
- DOI
10.1111/vde.13085