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- Title
Optimization of Heterologous Expression of Insulin Receptor-Related Receptor Ectodomain.
- Authors
Mozhaev, A. A.; Orsa, A. N.; Deyev, I. E.; Shvets, V. I.; Petrenko, A. G.
- Abstract
In this paper, we present an approach to optimize the heterologous expression of the receptor tyrosine kinase IRR, which further simplifies the purification of the IRR from the medium and increases the final yield. The approach proposed by us can find application in the biotechnological production of other large-scale recombinant proteins produced for medical purposes.
- Subjects
INSULIN receptors; RECOMBINANT proteins; PROTEIN-tyrosine kinases
- Publication
Doklady Biochemistry & Biophysics, 2019, Vol 485, Issue 1, p101
- ISSN
1607-6729
- Publication type
Article
- DOI
10.1134/S1607672919020017