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- Title
Biotechnological Method of Preparation and Characterization of Recombinant Antimicrobial Peptide Avicin A from Enterococcus avium.
- Authors
Balandin, S. V.; Finkina, E. I.; Nurmukhamedova, E. K.-A.; Tagaev, A. A.; Umnyakova, E. S.; Kokryakov, V. N.; Shvets, V. I.; Ovchinnikova, T. V.
- Abstract
Avicin A is a bacteriocin from the gram-positive bacterium Enterococcus avium. It exhibits a high microbicidal activity against bacteria of the genus Listeria, a causative agent of the severe human infection listeriosis. We developed a biotechnological method for obtaining avicin A and characterized its structure and biological activity. We also proposed a possible mechanism of the antimicrobial action of avicin A.
- Subjects
ENTEROCOCCUS; GRAM-positive bacteria; LISTERIA monocytogenes; LISTERIOSIS; LISTERIA; MORPHOLOGY
- Publication
Doklady Biochemistry & Biophysics, 2019, Vol 484, Issue 1, p42
- ISSN
1607-6729
- Publication type
Article
- DOI
10.1134/S1607672919010113