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- Title
Screening for Type 2 diabetes. Lessons from the ADDITION-Europe study.
- Authors
van den Donk, M.; Sandbaek, A.; Borch-Johnsen, K.; Lauritzen, T.; Simmons, R. K.; Wareham, N. J.; Griffin, S. J.; Davies, M. J.; Khunti, K.; Rutten, G. E. H. M.
- Abstract
Diabet. Med. 28, 1416-1424 (2011) Abstract Aims To describe and compare attendance rates and the proportions of people identified with Type 2 diabetes mellitus in people with previously unknown diabetes who participated in screening programmes undertaken in general practice in the UK, Denmark and the Netherlands as part of the ADDITION-Europe study. Methods In Cambridge, routine computer data searches were conducted to identify individuals aged 40-69 years at high risk of Type 2 diabetes using the Cambridge Diabetes Risk Score. In Denmark, the Danish Diabetes Risk Score was mailed to individuals aged 40-69 years, or completed by patients visiting their general practitice. In the Netherlands, the Hoorn Symptom Risk Questionnaire was mailed to individuals aged 50-69 years. In these three centres, high-risk individuals were invited to attend subsequent steps in the screening programme, including random blood glucose, HbA1c, fasting blood glucose and/or oral glucose tolerance test. In Leicester, eligible people aged 40-69 years were invited directly for an oral glucose tolerance test. In all centres, Type 2 diabetes was defined according to World Health Organization 1999 diagnostic criteria. Results Attendance rates ranged from 20.2% (oral glucose tolerance test in Leicester without pre-stratification) to 95.1% (random blood glucose in opportunistic screening in Denmark in high-risk people). The percentage of people with newly detected Type 2 diabetes from the target population ranged from 0.33% (Leicester) to 1.09% (the Netherlands). Conclusions Screening for Type 2 diabetes was acceptable and feasible, but relatively few participants were diagnosed in all participating centres. Different strategies may be required to increase initial attendance and ensure completion of screening programmes.
- Subjects
EUROPE; UNITED Kingdom; EVALUATION of clinical trials; TYPE 2 diabetes diagnosis; MEDICAL screening; DIABETES; PEOPLE with diabetes; GLUCOSE tolerance tests; POPULATION; RISK assessment
- Publication
Diabetic Medicine, 2011, Vol 28, Issue 11, p1416
- ISSN
0742-3071
- Publication type
Article
- DOI
10.1111/j.1464-5491.2011.03365.x