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- Title
Initial series of magnetic resonance imaging (MRI)‐fusion targeted prostate biopsy using the first transperineal targeted platform available in the USA.
- Authors
Kosarek, Christopher D.; Mahmoud, Ali M.; Eyzaguirre, Eduardo J.; Shan, Yong; Walser, Eric M.; Horn, Gary L.; Williams, Stephen B.
- Abstract
Objectives: To describe a step‐by‐step guide for using the first transperineal targeted prostate biopsy platform available in the USA. Patients and Methods: A total of 32 men with elevated prostate‐specific antigen (PSA) levels were diagnosed with a region of interest on multiparametric magnetic resonance imaging (mpMRI) between February 2017 and January 2018. The transperineal targeted prostate biopsy procedure was accomplished via a transperineal approach and used a stepper, combined with advanced mpMRI/transrectal ultrasound fusion software, to perform targeted prostate biopsy. The detection of overall and clinically significant prostate cancer (PCa) was assessed as well as the rate of complications. Results: The median patient age was 68.0 years and the median PSA was 8.0 ng/mL. Two patients (6%) were active surveillance candidates and 16 (50%) had a prior negative prostate biopsy. The detection rates for overall and clinically significant PCa were 81% and 59%, respectively. The two candidates for active surveillance and eight of the patients with a prior negative prostate biopsy had clinically significant PCa confirmed on targeted biopsy. There were no peri‐operative complications. Conclusion: These results demonstrate the promising potential of the first transperineal targeted prostate biopsy platform in the USA as an alternative diagnostic method for PCa.
- Subjects
PROSTATE disease diagnosis; MAGNETIC resonance imaging; PROSTATE-specific antigen; ENDORECTAL ultrasonography; CLINICAL pathology; PROSTATE diseases
- Publication
BJU International, 2018, Vol 122, Issue 5, p909
- ISSN
1464-4096
- Publication type
Article
- DOI
10.1111/bju.14206