We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Pharmacokinetics and pharmacodynamics of a single dose of zoledronate in healthy dogs.
- Authors
MARTÍN-JIMÉNEZ, T.; DE LORIMIER, L.-P.; FAN, T. M.; FREISE, K. J.
- Abstract
The article characterizes the pharmacokinetics and pharmacodynamics of zoledronate in healthy, mature dogs using biomarkers of bone metabolism. Results of the study suggest that zoledronate would be an effective drug to treat dogs suffering from pathological bone resorptive conditions such as neoplastic bone diseases, given the similar biomarker responses in dogs and humans.
- Subjects
PHARMACOKINETICS; PHARMACODYNAMICS; DOGS; ANTINEOPLASTIC agents; BONE metabolism; BIOMARKERS; BONE diseases
- Publication
Journal of Veterinary Pharmacology & Therapeutics, 2007, Vol 30, Issue 5, p492
- ISSN
0140-7783
- Publication type
Article
- DOI
10.1111/j.1365-2885.2007.00883.x