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- Title
Stabilization of β-catenin induces lesions reminiscent of prostatic intraepithelial neoplasia, but terminal squamous transdifferentiation of other secretory epithelia.
- Authors
Gounari, Fotini; Signoretti, Sabina; Bronson, Roderick; Klein, Ludger; Sellers, William R.; Kum, Jennifer; Siermann, Anja; Taketo, Makoto M.; von Boehmer, Harald; Khazaie, Khashayarsha
- Abstract
Presents a study that examined the role of the stabilization of β-catenin in inducing lesions reminiscent of prostate intraepithelial neoplasia (PIN). List of secretory epithelia; Association of the stabilization with the genesis of colorectoral neoplasms; Results of the recombination of a single β-catenin allele.
- Subjects
EPITHELIUM; TUMORS
- Publication
Oncogene, 2002, Vol 21, Issue 26, p4099
- ISSN
0950-9232
- Publication type
Article
- DOI
10.1038/sj.onc.1205562