We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Efficacy Of Oral Brush Cytology In The Detection Of Oral Malignant And Premalignant Lesions.
- Authors
Sharma, Shweta; Mittal, Anjana; Saxena, H. B.
- Abstract
Introduction : Oral cancers account for approximately 3% of all malignancies and is a significant worldwide health problem. Globally, oral cancers are one of the 10 most common cancers and accounts for almost 40% of all cancers in Indian subcontinent. A key factor in the lack of improvement in prognosis is the fact that a significant proportion of oral squamous cell carcinomas are not diagnosed and treated until they reach an advanced stage. Material and Method: The present study has been carried out on 50 patients suffering from oral cavity lesion. In all patients oral brush cytology using a toothbrush was done prior to a planned surgical biopsy. The study was done to assess the efficacy of oral brush cytology in detecting the premalignant and malignant lesions and its use as an early diagnostic aid. Result: 25 Cases were true positive on both histopathology and oral brush cytology. 20 Cases were true negative and 5 Cases were suspicious for malignancy on brush cytology, they were diagnosed as malignant on further histopathological examination. A sensitivity of 80%, specificity of 100%, negative predictive value was 83.3%, positive predictive value was 100% and accuracy was 90%. Conclusion: Oral brush cytology is an accurate diagnostic tool that plays a significant role in early cancer detection. It is also useful as a screening procedure for a high risk population or also for the clinical follow up.
- Subjects
SOUTH Asia; PRECANCEROUS conditions; TOOTHBRUSHES; SQUAMOUS cell carcinoma; CYTOLOGY; EARLY detection of cancer; ORAL cancer
- Publication
National Journal of Integrated Research in Medicine, 2018, Vol 9, Issue 6, p13
- ISSN
2230-9969
- Publication type
Article