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- Title
Actividad antimicrobiana de la melatonina y su impacto en la odontología.
- Authors
Castro Sánchez, Carlos Andrés; Villamil Poveda, Jean Carlos; Gamboa, Fredy; García Robayo, Dabeiba Adriana
- Abstract
Background: Melatonin is a hormone produced by vertebrate organisms, invertebrates, and plants. It is important in dentistry because it participates in osseointegration and immunomodulation processes. In addition, there are reports suggesting a possible antibacterial activity of melatonin. Purpose: To evaluate the antibacterial effect of melatonin on Streptococcus mutans CIO315, Staphylococcus aureus CIO613, Staphylococcus epidermidis CIO615, and Escherichia coli CIO465. Methods: This experimental study was carried out through the Mueller-Hinton agar dilution method. 43 to 3 μmol melatonin concentrations were analyzed on a 0.5 McFarland adjusted suspension of each strain. Finally a 1 μl of each microorganism was spread on the agar and incubated at 37 °C for 24 and 48 h. Results: Melatonin showed an antibacterial effect against the four bacteria studied with a 43 μmol mmolconcentration at 24 and 48 h. Conclusions: Melatonin has excellent antimicrobial activity against Streptococcus mutans CIO315, Staphylococcus aureus CIO613, Staphylococcus epidermidis CIO615, and Escherichia coli CIO465 at a concentration of 43 μmol, indicating that it could be an option in the prevention and treatment of oral diseases such as dental caries and periodontitis.
- Publication
Universitas Odontológica, 2014, Vol 33, Issue 71, p53
- ISSN
0120-4319
- Publication type
Article
- DOI
10.11144/Javeriana.uo33-71.aami