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- Title
Recombinant tissue plasminogen activators (rtPA): A review.
- Authors
Gurman, P; Miranda, OR; Nathan, A; Washington, C; Rosen, Y; Elman, NM
- Abstract
The article offers information on thrombolytic diseases which are considered the number one causes of deaths in the world. The responsibility of tissue plasminogen activator (tPA) for the degradation of thrombus formed during the coagulation process, is stated. It explores the novel clinical applications of recombinant tissue plasminogen activators (rtPAs) including frostbite, submacular hemorrhage, and pediatric empyema. The impact of rtPAs on clinical conditions is cited.
- Subjects
TISSUE plasminogen activator; FIBRINOLYTIC agents; THROMBOLYTIC therapy; CIRCULATING anticoagulants; DRUG therapy; HEMORRHAGE
- Publication
Clinical Pharmacology & Therapeutics, 2015, Vol 97, Issue 3, p274
- ISSN
0009-9236
- Publication type
Article
- DOI
10.1002/cpt.33