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- Title
How is insulin-like growth factor-1 correlated with retinopathy of prematurity?
- Authors
Jafari, Nahid; Moghadam, Arezoo Karimi; Taleghani, Naeeme Taslimi; Nezhad, Neda Hosseini; Motamed, Nima; Jalilvand, Ahmad
- Abstract
Background: Evaluation of insulin-like growth factor-1 (IGF-1) association with retinopathy of prematurity (ROP) is our object. Materials and Methods: This study was conducted on IGF-1 levels of 40 neonates <34 weeks gestational age and 2000 g at 1st week and 4--6 weeks after birth. All participants were evaluated for ROP after 31 weeks of gestation. Results: IGF-1 levels showed a significant difference between neonates ≤1500 and 1500--2000 g (1 and 4--6 weeks, P = 0.008, P = 0.039, respectively). No significant association was found between IGF-1 and ROP. Conclusion: Finding a meaningful association between IGF-1 and ROP requires consideration of factors affecting the IGF-1.
- Subjects
SOMATOMEDIN; GESTATIONAL age; RETROLENTAL fibroplasia; RISK assessment; DESCRIPTIVE statistics; DISEASE risk factors
- Publication
Journal of Research in Medical Sciences, 2021, p1
- ISSN
1735-1995
- Publication type
Article
- DOI
10.4103/jrms.JRMS_501_20