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- Title
Kidney allograft failure due to acute phosphate nephropathy associated with severe secondary hyperparathyroidism.
- Authors
Wong, Ping-Nam; Chan, Alice N. H.; Lo, Kin-Yee; Wong, Yuk-Yi; Mak, Siu-Ka; Wong, Andrew K. M.
- Abstract
Intratubular calcification is a common finding in renal allografts. However, possible harmful effect of this calcification is not well recognized, and allograft failure purely due to this condition has not been reported. We report a kidney transplant recipient who suffered from severe secondary hyperparathyroidism and unexplained early allograft failure. A diagnosis of acute phosphate nephropathy was made subsequently based on serial allograft biopsy findings. This case calls for a high index of suspicion to look for this rare cause of allograft dysfunction among high-risk patients. It also highlights the importance of good calcium–phosphate control before renal transplantation.
- Subjects
KIDNEY diseases; KIDNEY transplantation; HYPERPARATHYROIDISM; CALCIFICATION; HOMOGRAFTS; BIOPSY
- Publication
NDT Plus, 2011, Vol 4, Issue 5, p324
- ISSN
1753-0784
- Publication type
Article