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- Title
Effectiveness of Low Dead Space Syringes for Reducing the Risk of Hepatitis C Virus Acquisition Among People Who Inject Drugs: Findings From a National Survey in England, Wales, and Northern Ireland.
- Authors
Trickey, Adam; Croxford, Sara; Emanuel, Eva; Ijaz, Samreen; Hickman, Matthew; Kesten, Joanna; Thomas, Clare; Edmundson, Claire; Desai, Monica; Vickerman, Peter
- Abstract
Syringes with attached needles (termed fixed low dead space syringes [LDSS]) retain less blood following injection than syringes with detachable needles, but evidence on them reducing blood-borne virus transmission among people who inject drugs (PWID) is lacking. Utilizing the UK Unlinked Anonymous Monitoring cross-sectional bio-behavioral surveys among PWID for 2016/18/19 (n = 1429), we showed that always using fixed LDSS was associated with 76% lower likelihood (adjusted odds ratio = 0.24, 95% confidence interval [CI]:.08–.67) of recent hepatitis C virus infection (RNA-positive and antibody-negative) among antibody-negative PWID compared to using any syringes with detachable needles.
- Subjects
NORTHERN Ireland; ENGLAND; WALES; HEPATITIS C prevention; SYRINGES; CONFIDENCE intervals; CROSS-sectional method; SURVEYS; ODDS ratio
- Publication
Clinical Infectious Diseases, 2022, Vol 75, Issue 6, p1073
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/ciac140