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- Title
Are quality of family life and disease severity related in childhood atopic dermatitis?
- Authors
Ben-Gashir, MA; Seed, PT; Hay, RJ
- Abstract
Abstract Background Atopic dermatitis (AD) can be traumatizing to family life. Little is known about the relationship between quality of life in AD and disease severity. Objective To document family quality of life and relate this to severity of AD in children, for a 6-month period from a given point in time. Study design These data are part of a longitudinal study conducted in two parts of the UK to investigate risk factors for AD severity and its impact on quality of life. Subjects and methods The targeted population comprised children with AD aged 5–10 years in a primary-care setting. The general practitioners identified potential subjects and the UK diagnostic criteria for AD were used to verify the diagnosis. Both the children and their parents were interviewed. Eczema severity was assessed using a modified form of the SCORAD (SCORe Atopic Dermatitis) Index (SCORAD-D) from which parents’ score of itching and sleep loss were excluded. The quality of family life was quantified by the Dermatitis Family Impact (DFI) questionnaire. These two parameters were evaluated on two occasions 6 months apart. Analysis Multiple regression analysis was used to investigate the relationship between the quality of family life and the severity of the AD in the children, at a specific point in time and over the following 6-month period. Results Of the 116 children attending the first visit, mean age 8 years, 106 attended the second visit (91%) and were included in the analysis. Quality of family life was shown to be significantly affected in 48 (45%) cases at the first visit and 38 (36%) cases at the second visit. The initial means of the DFI and SCORAD-D were 2.4 and 8.2, respectively. Six months later the mean final DFI and SCORAD-D were 1.9 and 7.7, respectively. Using multiple regression on the first and second visits, each unit increase in SCORAD-D was associated with 0.21 [95% confidence interval (CI) 0.06–0.37 P = 0.008] and 0.37 (95% CI...
- Subjects
ATOPIC dermatitis; ECZEMA in children; EPIDEMIOLOGY
- Publication
Journal of the European Academy of Dermatology & Venereology, 2002, Vol 16, Issue 5, p455
- ISSN
0926-9959
- Publication type
Article
- DOI
10.1046/j.1468-3083.2002.00495.x