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- Title
Oxidative stress resistance and fitness-compensatory response in vancomycin-intermediate Staphylococcus aureus (VISA).
- Authors
Tan, Xin-Ee; Neoh, Hui-min; Cui, Longzhu; Hiramatsu, Keiichi; Jamal, Rahman
- Abstract
In this study, vancomycin-intermediate Staphylococcus aureus (VISA) cells carrying vraS and (or) graR mutations were shown to be more resistant to oxidative stress. Caenorhabditis elegans infected with these strains in turn demonstrated lower survival. Altered regulation in oxidative stress response and virulence appear to be physiological adaptations associated with the VISA phenotype in the Mu50 lineage.
- Subjects
STAPHYLOCOCCUS aureus; CAENORHABDITIS elegans
- Publication
Canadian Journal of Microbiology, 2019, Vol 65, Issue 8, p623
- ISSN
0008-4166
- Publication type
Article
- DOI
10.1139/cjm-2019-0048