We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Post percutaneous coronary intervention hemoglobin levels predict in-hospital mortality in patients with STEMI treated with primary percutaneous coronary intervention.
- Authors
Zeren, Gönül; Avcı, İlhan İlker; Şimşek, Barış; Sungur, Azmi; Çınar, Tufan; Tanık, Veysel Ozan; Genç, Duygu; Çinier, Göksel; Karabay, Can Yücel
- Abstract
Objective: In this study, we aimed to determine whether admission hemoglobin versus post-percutaneous coronary intervention (PCI) hemoglobin level at 24 hours is a predictor of in-hospital mortality for patients with ST elevation myocardial infarction (STEMI) without evidence of clinical hemorrhage who underwent primary PCI. Methods: In this study, we included 1,444 consecutive patients with STEMI who underwent primary PCI at a tertiary heart hospital. The primary outcome of the study was the in-hospital all-cause mortality. We used the penalized maximum likelihood estimation (PMLE) logistic regression method to examine the relationship between primary outcome and candidate predictors. Results: In total, 172 (11.9%) patients died during the in-hospital course. According to a PMLE logistic regression analysis, age, KILLIP class ≥2, pre-PCI thrombolysis in myocardial infarction (TIMI) flow <3, systolic blood pressure, creatinine, glycoprotein IIb/IIIa inhibitor use, and post-PCI hemoglobin levels at 24 hours were predictors of in-hospital mortality. The relative importance of post-PCI hemoglobin at 24 hours (contributing 6% of the explainable outcome in the model) was significantly higher than admission hemoglobin (contributing only 0.1% of the explainable outcome in the model). Conclusion: This study demonstrated that post-PCI hemoglobin levels were independently associated with in-hospital survival in patients with STEMI without evidence of bleeding following primary PCI. In addition, post-PCI hemoglobin was a better predictor of in-hospital mortality than admission hemoglobin for patients with STEMI who underwent primary PCI.
- Subjects
PERCUTANEOUS coronary intervention; ST elevation myocardial infarction; HOSPITAL mortality; HEMOGLOBINS; SYSTOLIC blood pressure
- Publication
Anatolian Journal of Cardiology / Anadolu Kardiyoloji Dergisi, 2021, Vol 25, Issue 9, p623
- ISSN
2149-2263
- Publication type
Article
- DOI
10.5152/AnatolJCardiol.2021.07282