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- Title
HAlign 3: Fast Multiple Alignment of Ultra-Large Numbers of Similar DNA/RNA Sequences.
- Authors
Tang, Furong; Chao, Jiannan; Wei, Yanming; Yang, Fenglong; Zhai, Yixiao; Xu, Lei; Zou, Quan
- Abstract
HAlign is a cross-platform program that performs multiple sequence alignments based on the center star strategy. Here we present two major updates of HAlign 3, which helped improve the time efficiency and the alignment quality, and made HAlign 3 a specialized program to process ultra-large numbers of similar DNA/RNA sequences, such as closely related viral or prokaryotic genomes. HAlign 3 can be easily installed via the Anaconda and Java release package on macOS, Linux, Windows subsystem for Linux, and Windows systems, and the source code is available on GitHub (https://github.com/malabz/HAlign-3).
- Subjects
JAVA (Indonesia); PROKARYOTIC genomes; SEQUENCE alignment; VIRAL genomes; DNA; SOURCE code; DNA polymerases
- Publication
Molecular Biology & Evolution, 2022, Vol 39, Issue 8, p1
- ISSN
0737-4038
- Publication type
Article
- DOI
10.1093/molbev/msac166