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- Title
Estimating TimeTrees with MEGA and the TimeTree Resource.
- Authors
Mello, Beatriz
- Abstract
The main outcome of molecular dating, the timetree, provides crucial information for understanding the evolutionary history of lineages and is a requirement of several evolutionary analyses. Although essential, the estimation of divergence times from molecular data is frequently regarded as a complicated task. However, establishing biological timescales can be performed in a straightforward manner, even with large, genome-wide data sets. This protocol presents all the necessary steps to estimate a timetree in the program MEGA X. It also illustrates how the TimeTree resource can be a useful tool to obtain chronological information based on previous studies, therefore yielding calibration boundaries.
- Publication
Molecular Biology & Evolution, 2018, Vol 35, Issue 9, p2334
- ISSN
0737-4038
- Publication type
Article
- DOI
10.1093/molbev/msy133