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- Title
Chemistry of an Unexplored Heterocyclic Ring System: Versatile Synthesis of 5-Aryl-2,3,4-benzothiadiazepine 2,2-dioxides.
- Authors
Fetter, József; Bertha, Ferenc; Molnár, Balázs; Volk, Balázs; Simig, Gyula
- Abstract
The article gives insight into the synthetic approach of a practically new heterocyclic ring system, 2,3,4-benzothiadiazepines. Starting from the easily available phthalides, an efficient synthesis of 5-aryl-2,3,4-benzothiadiazepine 2,2-dioxides is described here. Owing to their close structural similarity to 2,3-benzodiazepines and 2,3-benzodiazepine-4-ones, two well-known bioactive compound families, the new derivatives can be of importance in medicinal chemistry.
- Subjects
HETEROCYCLIC compounds; BENZENE compound synthesis; AZEPINES; HETEROCYCLIC compounds synthesis; PHTHALIDES; BIOACTIVE compounds
- Publication
Journal of Heterocyclic Chemistry, 2015, Vol 52, Issue 4, p1136
- ISSN
0022-152X
- Publication type
Article
- DOI
10.1002/jhet.2141