We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
A 22-year-old woman with lower limb arteriopathy. Buerger’s disease, or methamphetamine- or cannabis-induced arteritis?
- Authors
Leithäuser, Boris; Langheinrich, Alexander C.; Rau, Wigbert S.; Tillmanns, Harald; Matthias, F. Reinhard
- Abstract
This case report describes a 22-year-old woman with severe arterial ischemia leading to claudication and ulceration of the feet, presumably due to long-term abuse of amphetamine derivates, such as “speed” or “ecstasy,” and cannabis. Known causes for peripheral occlusive disease, such as atherosclerosis, vasculitis, or collagen vascular disease, were excluded. Laboratory test results did not show evidence of risk factors for thromboembolic diseases. Conventional angiography and magnetic resonance-angiography showed occlusions of medium- and small-sized arteries of both calves and feet. In the past, vasculitis-like arteriopathy was attributed to the abuse of amphetamines as well as of cannabis. However, amphetamines have been reported to be associated with necrotizing vasculitis mainly of cerebral arteries. Therefore, the abuse of methamphetamine or “ecstasy” also appears to play a role in the development of peripheral arterial occlusions and seems to have broad similarities with Buerger’s disease.
- Subjects
METHAMPHETAMINE; CANNABIS (Genus); DRUG abuse; ISCHEMIA; BLOOD circulation disorders; VASCULAR diseases; VASCULITIS; ANGIOGRAPHY
- Publication
Heart & Vessels, 2005, Vol 20, Issue 1, p39
- ISSN
0910-8327
- Publication type
Article
- DOI
10.1007/s00380-004-0769-5