We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Quantitative Changes in Pro-Oncogenic and Tumor-Suppressing MicroRNA in the Regional Lymph Node during Photodynamic Therapy of Experimental Breast Cancer.
- Authors
Kabakov, A. V.; Kazakov, O. V.; Poveshchenko, A. F.; Cherkas, V. N.
- Abstract
We studied quantitative changes in microRNAs in the axillary lymph node (regional lymph node of the mammary gland) and in the breast tumor tissue. The quantity of pro-oncogenic microRNAs (miR-21 and miR-221) in the regional lymph node decreased in the group after photodynamic therapy of the breast cancer. At the same time, the quantity of pro-oncogenic miR-27a remained decreased in this group, as well as in the group with breast cancer without treatment. The quantity of tumor-suppressing miR-429 in the regional lymph node after photodynamic therapy of breast cancer remained at the same level with the quantity in the group of rats with breast cancer without treatment.
- Subjects
PHOTODYNAMIC therapy; LYMPH nodes; BREAST cancer; BREAST; AXILLA; MICRORNA; MAMMARY glands
- Publication
Bulletin of Experimental Biology & Medicine, 2024, Vol 176, Issue 4, p491
- ISSN
0007-4888
- Publication type
Article
- DOI
10.1007/s10517-024-06053-8