We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Putative Role of Ligands of DNIC in the Physiological Action of the Complex.
- Authors
Titov, V. Yu.; Dolgorukova, A. M.; Osipov, A. N.; Kochish, I. I.
- Abstract
In a relatively isolated system of avian embryo, the metabolism of NO, a component of the dinitrosyl iron complexes (DNIC), the main NO donor in most tissues, depends on the ligands that make up the complex. This fact corroborates the earlier hypothesis that these ligands perform a regulatory function in NO metabolism. It is also shown that nitrite injected into the embryo is not oxidized to nitrate like NO in DNIC, but is accumulated outside the amniotic sac. Normally, nitrite is present in an embryo in trace amounts. These facts suggest that NO in the embryo is transferred from the donor molecule to a target in the embryo tissues further transformed with minimum oxidation to nitrite.
- Subjects
LIGANDS (Biochemistry); EMBRYO transfer; EMBRYOS; NITRIC oxide
- Publication
Bulletin of Experimental Biology & Medicine, 2021, Vol 171, Issue 5, p606
- ISSN
0007-4888
- Publication type
Article
- DOI
10.1007/s10517-021-05278-1