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- Title
Pharmacokinetic Properties of a New Glutamic Acid Derivative Glutaron.
- Authors
Smirnova, L.; Ryabukha, A.; Kuznetsov, K.; Suchkov, E.; Perfilova, V.; Tyurenkov, I.
- Abstract
Inhomogenous distribution of glutaron in organs and tissues was found after intravenous and peroral administration: the agent demonstrated high affi nity to organs with high degree of vascularization (lungs and heart) and elimination (kidney). Glutaron easily penetrates through the blood-brain barrier, which is consistent with its concentration in the adipose tissue.
- Subjects
GLUTAMIC acid; PHARMACOKINETICS; DRUG administration; BLOOD-vessel development; BLOOD-brain barrier
- Publication
Bulletin of Experimental Biology & Medicine, 2015, Vol 159, Issue 2, p229
- ISSN
0007-4888
- Publication type
Article
- DOI
10.1007/s10517-015-2929-2