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- Title
Direction determination in the minus-end-directed kinesin motor ncd.
- Authors
Sablin, Elena P.; Case, Ryan B.; Dai, Shirieko C.; Hart, Cynthia L.; Ruby, Aaron; Vale, Ronald D.; Fletterick, Robert J.
- Abstract
Presents research which showed that the ncd neck is essential for minus-end-directed motility in motor proteins of the kinesin superfamily. Amino-acid identity in their motor catalytic cores; Comparison of crystal structures of conventional kinesin and ncd; Mutagenesis of the ncd neck; Comparison of the kinesin neck and the ncd neck; Importance of distinct neck architectures.
- Subjects
KINESIN; MOLECULAR rotation of proteins; MUTAGENESIS; CELL motility; METABOLISM
- Publication
Nature, 1998, Vol 395, Issue 6704, p813
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/27463