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- Title
Impact of Pesticides on Cancer and Congenital Malformation: A Systematic Review.
- Authors
Melanda, Viviane Serra; Galiciolli, Maria Eduarda A.; Lima, Luíza S.; Figueiredo, Bonald C.; Oliveira, Cláudia S.
- Abstract
Pesticide exposure has deleterious effects on human health and development; however, no review has been conducted on human exposure to pesticides and the risk of congenital malformations and cancer in the same cohort. We systematically reviewed the evidence for this relationship following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. Four databases, namely, PubMed, Scopus, Cochrane Library, and BVS, were searched for studies deposited till July 2020 that examined the influence of pesticide exposure on congenital malformations and cancer outcomes in the same cohort. Seven studies were systematically included in this review. Among these, four were case–control studies, two were cross-sectional studies, and one was a longitudinal cohort study. The sources of contamination were food, water, or exposure during agricultural work. A link between the occurrence of cancer, congenital malformations, and exposure to pesticides was observed in most studies.
- Subjects
HUMAN abnormalities; PESTICIDES; FOOD contamination; POLLUTANTS; CROSS-sectional method; CASE-control method
- Publication
Toxics, 2022, Vol 10, Issue 11, p676
- ISSN
2305-6304
- Publication type
Article
- DOI
10.3390/toxics10110676