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- Title
THE IMPORTANCE OF GUT-BRAIN AXIS IN THE PATHOGENESIS OF AUTISM SPECTRUM DISORDERS.
- Authors
NEACŞU, ROXANA; CERLINCĂ, ANCA; RAD, FLORINA
- Abstract
In recent years, there has been increasing interest in the study of the intestinal microbiota in autism spectrum disorders (ASD) children, and the possible implication of gut-brain axis in the etiology of ASD. Current literature comes with impressive data regarding the possible relationship between intestinal flora abnormalities and how these changes impact brain development through increased neuroinflammation and oxidative stress. The aim of this article is to present the current knowledge on the link between intestinal flora and the brain as a bidirectional communication pathway and how intestinal microbiota changes could be involved in the pathogenesis of autism.
- Subjects
AUTISM spectrum disorders; PATHOLOGY; GUT microbiome; ETIOLOGY of diseases; INFLAMMATION
- Publication
Romanian Journal of Child & Adolescent Psychiatry, 2019, Vol 7, Issue 1/2, p48
- ISSN
2360-185X
- Publication type
Article