We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Bone turnover markers in monitoring the early response to bisphosphonates treatment.
- Authors
LI Yizhong; GUO Liangrui; ZHUANG Huafeng; CAI Siqing; PAN Yuancheng
- Abstract
Objective To monitor the early response to bisphosphonates treatment with bone turnover markers. Methods Serum (β-CTX P1NP were monitored for 60 postmenopausal women before and 16 weeks after the bisphosphonates treatment, in order to evaluate the efficacy of the treatment. Results β-CTX was 0.390 ±0.230 ng/ml and P1NP was 51.445 ± 25.955 ng/ml before the bisphosphonates treatment. Bone turnover was high in 24 patients and normal in 36 before the treatment. β-CTX was 0.133 ± 0.120 ng/ml and P1NP was 18.853 ± 10.225 ng/ml after the bisphosphonates treatment. The significant reduction in β-CTX and P1NP was present. The efficacy of the treatment was 95%. Conclusion The measurement of (β-CTX and P1NP are effective method for monitoring the bisphosphonates treatment.
- Publication
Chinese Journal of Osteoporosis, 2014, Vol 20, Issue 10, p1175
- ISSN
1006-7108
- Publication type
Article