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- Title
Expression of atrial natriuretic factor (ANF) during Xenopus cardiac development.
- Authors
Small, Eric M.; Krieg, P.A.
- Abstract
We have isolated the Xenopus orthologue of the atrial natriuretic factor (ANF) gene. Characterization of embryonic expression indicates that the ANF gene is initially expressed throughout the developing myocardium at the late heart tube stage (about stage 32). This is in contrast to all previously characterized Xenopus cardiac differentiation markers that are first expressed in the cardiogenic plate at approximately stage 27. ANF expression becomes restricted exclusively to the atrium at about stage 47, long after the commencement of beating and the original formation of the atrial and ventricular compartments, but shortly after septation of the single atrium into two distinct atria.
- Subjects
XENOPUS; ATRIAL natriuretic peptides; MYOCARDIUM; EMBRYOLOGY; GENES; HEART
- Publication
Development Genes & Evolution, 2000, Vol 210, Issue 12, p638
- ISSN
0949-944X
- Publication type
Article
- DOI
10.1007/s004270000104